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Figure 5 Relation between the immunohistochemical grade for von Willebrand factor (vWF) and the degree of platelet adhesion/thrombus formation in the endocardium. Each symbol indicates a right or left atrial appendage obtained from a cardiac patient. There was a significant correlation between the two variables (r = 0.52, p < 0.01 by Spearman rank correlation) only when the cases who had received warfarin-treatment (closed symbols) were excluded.