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Figure 2 T_CEC during ischemia in one animal: comparison with normal range and the extent of myocardium at risk. Ischemic T_CEC from one animal during ischemia (black thick line) is plotted against the normal range of T_CEC (mean ± SD, striped region) for unfolded left ventricle (LV) circumference (Y-axis). During left anterior descending coronary artery ischemia, prolonged T_CEC occurs in both apical and midseptal segments, whereas in the rest of the segments T_CEC did not exceed the normal range. The black bar on the right represents LV from the same apical view, reconstructed from the stained cardiac specimen: myocardium at risk corresponds to the unstained area (white zone), while normally perfused myocardium corresponds to the stained area (black zone). Note the good topographical match between the region with prolonged T_CEC and the extent of myocardium at risk (bS = basal septal; mS = midseptal; aS = apical septal; aL = apical lateral; mL = mid lateral; bL = basal lateral).