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Figure 3 Line graphs show forearm blood flow at rest and during reactive hyperemia in patients with essential hypertension before (0 weeks) and after 2, 4, 8, 12, 24 and 48 weeks of treatment with the angiotensin-converting enzyme inhibitor imidapril and the calcium antagonist amlodipine. Imidapril augmented RH after 12 weeks of treatment. There was no significant difference in RH at 12, 24 and 48 weeks. Amlodipine did not alter RH for each treatment period.