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Figure 2 Changes in vessel dimension and vasomotor response to successive Ach infusions are shown as the average of per patient means (n = 29). (A) Plot of mean vessel diameter in mm at control and after Ach infused at 10^–6 to 10^–4M. Baseline values (M ± SE) are shown as closed circles/solid line; values from follow-up study after cholesterol lowering are shown as open squares/dashed line. (B) Plot of mean change (in mm) in vessel diameter from control upon Ach infusion at graded doses (M ± SE). (C) Plot of mean percent change in vessel diameter from control upon Ach infusion at graded doses (M ± SE). Ach = acetylcholine. Solid circle = baseline; Shaded square = follow-up.