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Figure 4 Upper panels: Two-dimensional echo apical four-chamber images in the sheep, with no MR at baseline (left), trace MR acutely after coronary ligation (middle) and apical leaflet tenting with moderate MR in the chronic phase eight weeks later with prominent LV remodeling (right). Lower panels: Views of the 3D reconstructions from the apex (Fig. 1F). With LCX obtuse marginal branches 2 and 3 ligation, the PMs, especially the ischemic medial one (green), migrate away from the annular reference (red), stretching the leaflets over a larger distance. This shift is mild in the acute stage, without LV remodeling, and larger in the chronic stage after remodeling. Other abbreviations as in Figure 1.