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Figure 5 Endothelium dependent elaxation of microvessels. Relaxation was induced by adenosine diphosphate (ADP). Microvessels were taken from the ischemic area (LCX, dotted lines) and the normal area (LAD, uninterrupted lines) from pigs that were treated with intracoronary VEGF, intracoronary VEGF + L-NAME or vehicle. * LCX microvessels from intracoronary VEGF + L-NAME treated animals had a lower response to maximum dose of ADP than the intracoronary VEGF group (p = 0.011).