Click on image to view larger version.

Figure 4 Time-related percent changes in LAD blood flow from the baseline state in response to various vasoactive agents: (a) acetylcholine, 0.05 µg/kg; (b) 5-HT, 1 µg/kg; (c) ISDN, 10 µg/kg; (d) adenosine, 10 µg/kg. Control group (x); ED group (open circle); and Drug group (closed circle) (n = 12, each). Values are means ± SEM. ^¥p < 0.01 by two-way ANOVA. p < 0.01 vs. 0 week at the same portion in the same condition. p < 0.01 vs. two weeks at the same portion in the same condition. ^@p < 0.01 vs. the Control group in the same experimental period. ^¶p < 0.01 vs. the Drug group in the same experimental period.