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Figure 4 The mRNA levels of ACE, AT1a receptor at 13 and 19 weeks old. Each mRNA level was corrected for an mRNA level of glyceraldehyde-3-phosphate-dehydrogenase and was then normalized to a mean value of age-matched control group, respectively. **p < 0.01 versus control group; p < 0.01 versus CAND(–) group. Values are means ± SEM. Hatched bar= control; solid bar= CAND(–); open bar= CAND(+). ACE = angiotensin-converting enzyme; mRNA = messenger RNA.