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Figure 1 Results (group means ± SEM) for Protocol 1: coronary artery stenosis stable coronary flow. (A) % Flow-time area and (B) Regional myocardial blood flow (RMBF) in endocardial (Endo) and epicardial (Epi) segments of the stenotic left anterior descending coronary artery bed for control and sildenafil-treated dogs. Black bars indicate controls; white bars indicate sildenafil. PreTreat = data obtained during the initial hour before randomization and treatment.