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Figure 4 LVmassI over time. Mean LVmassI is shown in the metoprolol CR/XL group and in the placebo group at baseline, five or seven weeks and six months after randomization. *The metoprolol CR/XL group versus the placebo group. Metoprolol CR/XL group versus baseline: p = 0.01; placebo group versus baseline: p = 0.005. CI = confidence interval; LVmassI = left ventricular mass index.