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Figure 2 Left panel. Angiogram in the right anterior oblique projection revealing a severe stenosis in the mid-left anterior descending coronary artery. (a) De novo lesion. (b) After initial stenting. (c) Stent restenosis (before treatment). (d) Immediately after treatment of in-stent restenosis (index procedure). (e) At six-month follow-up. A large diagonal branch and two small septal perforator side branches are always visualized. Right panel. Angiogram in the left anterior oblique projection with cranial angulation in a patient with a tight lesion in the proximal left anterior descending coronary artery (a to e, timing same as above). A diagonal branch—with severe ostium involvement—remained patent after initial stenting, occluded (without clinical sequelae) during treatment of in-stent restenosis (asterisk) and reappeared at follow-up (arrow).