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Figure 3 Relation between LV peak (+)dP/dt and action potential duration (APD90) during the steady state pacing experiments with sotalol and esmolol. In the sotalol experiments (left panel), there was a significant direct relation between APD and LV (+)dP/dt. By contrast, no such relation was seen in the esmolol experiments (right panel). LV = left ventricular.