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Figure 3 A) shows extensive coagulative necrosis and endothelial disruption with US power of 1.0 W/cm2 without PESDA (4,800x). B) shows endothelial pore formation with US power of 0.8 W/cm2 without PESDA (5,400x). C) (8,000x) shows no significant endothelial changes with US power of 0.6 W/cm2 as compared with control rat heart sections. D) shows a control rat heart section (4,800x).