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Figure 3 PASP response to exercise. Discrimination between controls and HAPE-S subjects by their PASP response to exercise estimated by Doppler echocardiography. HAPE-S, subjects susceptible to high-altitude pulmonary edema (n = 9), CONTROLS, control subjects (n = 11). No significant differences at rest between both groups (p = 0.28). *Mean maximal PASP in controls (36 ± 3 mm Hg) vs. HAPE-S (55 ± 11 mm Hg) subjects, p < 0.002.