Click on image to view larger version.

Figure 1 Left, Bar graph showing BrdU uptake in optical density units as measured by colorimetry. *p < 0.05 vs. 0% FCS. p < 0.05 vs. 5% FCS. 0% FCS = BrdU uptake in cells not stimulated with FCS; 5% FCS = BrdU uptake in cells stimulated with 5% FCS; 5% FCS + BNP = BrdU uptake in cells coincubated in 5% FCS and BNP (10^–7 mol/liter). Right, Bar graph showing cGMP generation. *p < 0.05 vs. control. p < 0.05 vs. 3 and 9 h. LOD = limit of detection.