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Figure 5 Top panel: The effects of aortic constriction on the mean multibeat PRSW measurements (V_w and M_w) and single-beat M_w (SBM_w) estimates in Group II dogs. Neither multibeat nor single-beat estimates are sensitive to the increased afterload. There were no significant differences between multibeat and single beat M_w values, whether based on individual k values (measured) or a constant k value of 0.7 (calculated). Bottom panel: The corresponding volume-axis intercept (V_o) and slope (E_es) of the ESPVR, single-beat E_es (SBE_es) and PWR_max/EDV² data (see text). ESPVR = end-systolic pressure-volume relationship; M_w = slope of the PRSW relationship; PRSW = preload recruitable stroke work; PWR_max/EDV² = maximum left ventricular power divided by the square of end-diastolic volume. V_w = volume-axis intercept of the PRSW relationship. *p < 0.05 vs. control.