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Figure 2 Transstenotic pressure gradient (top), distal coronary pressure (middle) and percent blood flow velocity (bottom) values at the various steps of the protocol as indicated in Figure 1. Blood flow velocity was assumed to be zero during balloon coronary occlusion (dashed line). Despite very different flow values, distal coronary pressure was similar following adenosine and during maximal ST shift; by contrast, it was markedly lower during balloon coronary occlusion (* = p < 0.05 vs. baseline; = p < 0.05 vs. adenosine; = p < 0.05 vs. max ischemia).