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Figure 1 Forearm blood flow at rest and during reactive hyperemia in the normotensive control subjects (n = 47), hypertensive patients treated with calcium antagonists (n = 175), ACE inhibitors (n = 51), beta-blockers (n = 14) and diuretic agents (n = 10) and untreated hypertensive patients (n = 46). Reactive hyperemia was impaired in hypertensive patients as compared with normotensive subjects (p < 0.01). Reactive hyperemia was greater in hypertensive patients treated with ACE inhibitors than in those treated with calcium antagonists (p < 0.01), beta-blockers (p < 0.01) and diuretic agents (p < 0.05) and untreated hypertensive patients (p < 0.01). Reactive hyperemia was similar among calcium antagonist, beta-blocker, diuretic agent and untreated groups.