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Figure 2 Representative histologic sections stained with hematoxylin-eosin of the common carotid arteries from (a) a control rat subjected to only balloon injury; (b) a rat treated with 0.04 mg/kg simvastatin; (c) a rat treated with 4 mg/kg simvastatin; (d) a rat treated with 16 mg/kg simvastatin; (e) a rat treated with 40 mg/kg simvastatin; and (f) a rat treated with 40 mg/kg simvastatin plus local administration of mevalonate (10 mmol/liter).