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Figure 2 Time course of the effects of aerosolized iloprost on pulmonary vascular resistance (PVR). Patients were inhaling 14 to 17 µg iloprost within 15 min and the hemodynamic variables were measured at the indicated time points. Changes in PVR (percent) are shown as median and upper 95% confidence limits of the median. Asterisk indicates p < 0.05 vs. baseline.