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Figure 2 Pedigree of OHSU FDC-2. OHSU FDC-2 is comprised of two Caucasian families spanning five generations that includes 20 paternal (A) and 84 maternal (B) relatives. The index patient’s paternal grandmother (III-A) died from dilated cardiomyopathy at the age of 51 years. The geographic distribution of these families range from the Pacific Northwest to the Midwest and southern U.S. The number 19 below the subject symbol and the number in parentheses (#4) denote the number of known descendants and the number of screened subjects, respectively, not shown due to space limitations.