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Figure 3 Effect of the DD and II/ID genotypes on concentration-response curves for phenylephrine in the presence of angiotensin II (ANG II, 10 pmol/liter) or the solvent (CONTROL). Arterial segments were obtained from patients with DD genotype (n = 12) or the II/ID genotypes (n = 24) of the angiotensin I-converting enzyme. Mean value ± SEM is given. *p < 0.0001, two-factor ANOVA for repeated measures, ANG II vs. CONTROL. #p < 0.003, two-factor ANOVA for repeated measures, genotype DD vs. genotypes II/ID.