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Figure 5 Representative micrographs of plaque material from vein graft aspirates. (A) Fibrous cap (FC) overlying a lipid-rich necrotic core (NC) containing numerous cholesterol clefts (arrows, Movat Pentachrome, x200). (B) Section stained using the monoclonal antibody CD68/KP-1 (Dako Inc., Carpinteria, California) for recognition of resident macrophages (dark brown reaction product, x200). (C) Immunostaining of aspirate material with the antibody HHF-35 (Enzo Inc., Farmingdale, New York) for recognition of smooth muscle cells (brown reaction product); note the paucity of staining (x100). (D) Necrotic core with plaque hemorrhage (red cells and fibrin, x200). (E) Aspirate material showing strands of collagen (arrow, H&E stain, x200). (F) Lipid-rich core area with cholesterol clefts (arrows, H&E stain, x200).