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Figure 4 Selective inhibition of dephosphorylation. Four substrates of cyclic adenosine monophosphate (cAMP)-dependent protein kinase—troponin I (TnI), phospholamban (PL), glycogen synthase (Gly Syn) and cAMP-response element-binding protein (CREB)—are represented hypothetically coupled to separate protein phosphatases (designated PP-T, PP-P, PP-G and PP-C). Selective inhibition of PP-T would result in a selective increase in the phosphorylation of troponin I. PK-A = protein kinase.