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Figure 1 Characteristics of [3H]ryanodine binding to atrial tissue in patients with either atrial fibrillation (AF) or normal sinus rhythm (NSR). In patients with AF, there was a significant depression in the maximum number of binding sites (Bmax) in each atrium (by comparison with the value for the right atrium in patients with NSR). The dissociation constant (Kd) did not differ significantly among the three groups. R, right atrium; L, left atrium. Data are mean ± SD.