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Figure 5 Bar graph demonstrating the significant decrease in mean vessel area, which is the most important factor responsible for the considerable luminal loss "early" after transplantation. In contrast changes "late" after heart transplantation are shown to be characterized by a mean increase in vessel volume, resulting in a slight increase in lumen volume. White bars = plaque volume; black bars = lumen volume; shaded bars = vessel volume. **p < 0.001.