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Figure 4 Variability in circulating interleukin-6 (IL-6) levels in heart failure and control subjects. The degree of IL-6 variability was assessed by determining the coefficient of variation (CV) (see Methods) for daily, weekly and monthly IL-6 levels. Each data point shown reflects the CV for a given subject. Heart failure patients are depicted by closed diamonds, and healthy control subjects are depicted by open squares. The mean ± SEM of the CVs in each group are shown to the right of each scatter plot.

* = p < 0.05 compared with control subjects.