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Figure 1 Mortality from acute myocardial infarction (AMI) and stroke by season. Relative risks for high and low months are compared with the average of all seasons combined. There are significant winter peaks (AMI p < 0.001, stroke p < 0.001) and summer troughs (AMI p < 0.001, stroke p < 0.001) in cardiovascular disease mortality, with a large difference in AMI (9.8%) and stroke (14.3%) mortality between these two seasons.