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Figure 5 Systolic circumferential strain (top), external work (middle) and total work (bottom) during RA, LVbase and RVapex pacing, as measured at two sites: RVapex (striped bars) and LVbase (closed bars). Mean values ± SD from seven experiments are presented. *p < 0.05 compared with the same site during RA pacing, p < 0.05 compared with the same site during pacing at the RVapex and #p < 0.05 compared with the opposite region during pacing at the same site.