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Figure 2 Voxel gradient shading of normal coronary artery shown at two different angles on the sagittal plane (voxel size, 28 µm). Two anatomically different type of vasa vasorum are visualized. First-order vasa (arrow) originate from the main lumen of the coronary artery (arrow) running longitudinally along the adventitial surface of the artery. Second-order vasa (triangle) originate directly from the first-order vasa, and form a plexus circumferentially around the vessel wall, as arch arterioles.