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Figure 4 (A) Example of changes in systolic pressure to alterations in ventricular diastolic volume in a young and in an elderly patient. Data are derived from the same set of pressure volume loops shown in Figure 2. There is much greater sensitivity of systolic pressure to volume changes in the elderly patient, indicated by the steeper slope. (B) Group results showing effects of age on the slope of the systolic pressure LV end diastolic volume dependence (SBP_EDV). This relation slope increased significantly with age.