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Figure 1 Examples of M-mode echocardiograms, trans-mitral Doppler flow signals, and LV pressure tracings in anesthetized rats 20 weeks after sham surgery (top), or aortic banding, LVH (bottom). There is increased LV wall thickness in the LVH rats, accompanied by a restrictive mitral filling profile. Note the very diminutive A-wave in the mitral inflow trace at similar heart rate to that seen in the sham animals. Both LV systolic and diastolic pressures are elevated in the LVH rats.