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Figure 2 Schematic representation of the patency status of the LAD coronary artery. Black squares = zero flow; striped squares = periods with cyclic flows; open (white) squares = periods with optimal coronary perfusion. The time-point at which the peak hyperemic flow occurred (at the beginning of optimal reperfusion) is marked with an X. r-tPA = recombinant tissue plasminogen activator, alteplase.