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Figure 4 Scatterplots of the difference (PISA minus reference methods, y-axis) to the reference methods (x-axis) for calculation of ERO using the Doppler echocardiographic method (A) or two-dimensional method (B) as a reference. The patients with appropriate FC are represented by solid dots, and their 95% confidence interval is represented by the gray zone. The differences were not statistically different from zero. The open dots superimposed represent the five patients with an obtuse angle of the proximal FC region (>220°).