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Figure 1 Color-coded images and corresponding time–intensity plots (fitted to a gamma-variate function) in a Group I dog during hyperemia. At baseline (A), there is no difference in VI between the LAD and LCx beds. In the presence of a mild stenosis (transstenotic pressure gradient 14 mm Hg), VI in the LAD bed decreased compared with that in the LCx bed (B). The decrease was even greater (C) in the presence of a moderate stenosis (transstenotic pressure gradient 22 mm Hg). Open squares = LAD bed; solid squares = LCx bed.