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Figure 1 Scheme of presynaptic and postsynaptic sympathetic innervation. The norepinephrine (NE) analogue [11C]HED was used for measuring presynaptic reuptake of norepinephrine (UP), and the nonselective beta-blocker [11C]CGP 12177 was used for measuring postsynaptic beta-adrenoceptor (ß-AR) density.