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Figure 1 Time to detection of significant arrhythmia complications (SAC) after initiation of sotalol. The mean time to the earliest detection of clinically significant arrhythmia complications was 2.0 ± 1.9 days. The time to detection of new or increased ventricular arrhythmias was 2.9 ± 1.8 days, significant bradycardia 2.0 ± 1.8 days and excessively prolonged QTc intervals 3.3 ± 3.1 days. The time monitored in the hospital during sotalol therapy after its initiation was 4.7 ± 4.0 days in the total group.