A 69-year-old male with a background of hypertension and hyperlipidemia presented with acute ischemic-type chest pain at rest. Initial electrocardiography showed inferolateral territory ST-segment elevation, and he was treated as standard with intravenous fibrinolysis. Ninety minutes post-therapy, the patient underwent rescue coronary angioplasty, performed via the right radial artery, with a single drug-eluting stent placed in the proximal right coronary artery. Four hours post-angioplasty, the patient noticed blurred vision in his left eye, and examination revealed a superior medial quadrantanopia and reduced visual acuity (20/100). Fundoscopy demonstrated a white embolus (Hollenhorst plaque) in the inferior branch of the central retinal artery (A, arrow) with associated retinal edema.