Serial cardiac MRI was performed with a 1.5-T scanner (Avanto, Siemens, Erlangen, Germany) at baseline and 12 months of follow-up. Transverse images were acquired with an inversion recovery prepared dark blood HASTE sequence (repetition time [TR] 600 ms, echo time [TE] 26 ms, 6 mm slice thickness, 1.8 mm interslice gap, matrix 256 × 104). Cine bright-blood images in the 4- and 2-chamber long-axis planes were performed with a breath-hold balanced steady-state free precession sequence (true fast imaging with steady-state precession, TR 42 ms, TE 1.2 ms, fractional anisotropy 70°, 6 mm slice thickness, matrix 192 × 174). Cine breath-hold balanced steady-state free precession short-axis images then encompassed the entire LV from the base to the apex (stack of 10 sequential short-axis slices; TR 64 ms, TE 1 ms, fractional anisotropy 80°, 8 mm slice thickness, 1.6 mm interslice gap, matrix 192 × 132) to obtain an LVEF. To evaluate for myocardial edema, dark blood T2-weighted turbo spin echo short-axis images were obtained (TR 1,800 to 2,100 ms, TE 74 ms, 8 mm slice thickness, 4 mm interslice gap, matrix 256 × 175). Late gadolinium enhancement (LGE) images were obtained after 10 min of 0.2 mmol/kg injection of gadolinium (Gd-DTPA, Magnevist, Schering, Germany) with a T1-weighted inversion recovery-prepared multislice true fast imaging with steady-state precession sequence with magnitude and phase-sensitive reconstruction. Images were acquired sequentially in the short axis, followed by horizontal and vertical long-axis images (TR 700 ms, TE 1.0 ms, fractional anisotropy 40°, 8 mm slice thickness, 1.6 mm interslice gap, matrix 192 × 144). To quantify the myocardial mass of the LGE, the endocardial and epicardial borders of the short-axis view of the LV were manually traced. The computer-assisted detection algorithm defined LGE as any region with a signal intensity ≥2 SD above a reference remote myocardial region. The LGE mass was expressed as a percentage of the LV mass. Quantitative analysis was performed with dedicated computer software (CMR44, Release 3.0.0, Circle Cardiovascular Imaging, Calgary, Alberta, Canada).