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Letters to the editor |

Winter and cardiovascular mortality FREE

Paulo A Lotufo, MD, DrPH
[+] Author Information

American College of Cardiology

J Am Coll Cardiol. 1999;34(7):2150-2150. doi:10.1016/S0735-1097(99)00483-0
Published online

I read with interest the report by Sheth et al. (1) on seasonal variations of coronary heart disease and stroke mortality, and I would like to present a new analysis of data culled from an old Brazilian study performed in São Paulo, a city situated at the Tropic of Capricorn.

Between January 1932 and December 1941, Chiaverini and Rey (2) studied all deaths from congestive heart failure (CHF) confirmed by the city’s unique autopsy service. They concluded that most of the CHF deaths occurred during the winter, which in São Paulo runs from June to August. I examined the mortality data during a shorter period (July 1939 to December 1941), because there was better weather data, and confirmed Chiaverini and Rey’s results. In my analysis, CHF deaths were 28.8% higher during the winter months as compared with the summer months (December to February). Minimal monthly temperature (annual range 7.7 to 18.1°C) had a persistent association with CHF deaths (r = −0.31, p = 0.0456) after multiple linear regression analysis for humidity, hours of sunlight, temperature range and CHF mortality. These results from historic data are in concordance with a recent report analyzing coronary artery disease mortality in Hawaii (3), which is located at an equivalent latitude as São Paulo, but in the Northern Hemisphere. However, the most relevant finding from Chiaverini and Rey’s study is that most of the CHF cases were categorized as “nonatherosclerotic diseases.” During the 1940s in São Paulo (4), the etiology of CHF was rheumatic (23.6%), hypertensive heart disease (23.1%), atherosclerosis (20.6%), Chagas’ disease (10.8%) and syphilis (7.1%). Given these data, it is plausible to speculate that seasonal variations in cardiovascular mortality may be due to factors directly associated with impairment of myocardial contractility, such as arrhythmias and increasing blood pressure, rather than to factors more specifically related to rupture of coronary atherosclerotic plaque.

Funding: Fundaçāo de Amparo a Pesquisa do Estado de São Paulo (97/02424-8)

References

Sheth  T., Nair  C., Muller  J., Yusuf  S.; Increased winter mortality from acute myocardial infarction and stroke. the effect of age. J Am Coll Cardiol. 33 1999:1916-1919.
CrossRef | PubMed
Chiaverini  R., Rey  C.; Ensaio acerca das possiveis influencias metereologicas sobre a mortalidade cardiovascular. Rev Bras Med. 4 1947:673-680.
Seto  T.B., Mittleman  M.A., Davis  R.B., Taira  D.A., Kawachi  I.; Seasonal variations in coronary artery disease mortality in Hawaii. observational study. BMJ. 316 1998:1946-1947.
CrossRef | PubMed
Tranchesi  B., Dias  J.C., Nussenzveig  I., Tisi  O.G., Tranchesi  J., Lion  M.F.; A etiologia das cardiopatias em São Paulo (Brasil). Arq Bras Cardiol. 4 1951:31-44.
PubMed

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References

Sheth  T., Nair  C., Muller  J., Yusuf  S.; Increased winter mortality from acute myocardial infarction and stroke. the effect of age. J Am Coll Cardiol. 33 1999:1916-1919.
CrossRef | PubMed
Chiaverini  R., Rey  C.; Ensaio acerca das possiveis influencias metereologicas sobre a mortalidade cardiovascular. Rev Bras Med. 4 1947:673-680.
Seto  T.B., Mittleman  M.A., Davis  R.B., Taira  D.A., Kawachi  I.; Seasonal variations in coronary artery disease mortality in Hawaii. observational study. BMJ. 316 1998:1946-1947.
CrossRef | PubMed
Tranchesi  B., Dias  J.C., Nussenzveig  I., Tisi  O.G., Tranchesi  J., Lion  M.F.; A etiologia das cardiopatias em São Paulo (Brasil). Arq Bras Cardiol. 4 1951:31-44.
PubMed

Correspondence

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