One would surmise, on the basis of the aforementioned, that PH and “hyperkinetic heart syndrome” might have something in common, if they do not represent the same pathophysiological entity. Of note is that Gorlin et al. (5) remarked that “the high prevalence of all forms of hypertension, including systolic, labile, and sustained hypertension in these patients suggests a relationship between hypertension and hyperkinetic circulatory states,” with significant support from the published data. Also they found a “benign short-term and 20-year prognosis in the majority of patients with the idiopathic hyperkinetic heart syndrome” with occasions of regression, although they recommended beta-blockade particularly for patients with hypertension (5). Because Gorlin et al. found a high rate of “flow” murmurs on physical examination of their subjects and electrocardiogram left ventricular hypertrophy ((2),(3),(4),5), it might be useful to evaluate the University of California, San Diego twin/family database (1), with regard to the prevalence of these 2 items. Also in view of the follow-up study of the “hyperkinetic heart syndrome” of Gorlin et al. (5), it might be advisable to have a follow-up study of PH in due time to complement the cross-sectional investigation by Davis et al. (1).