CLINICAL RESEARCH: CARDIAC IMAGING
Noninvasive Assessment of Plaque Morphology and Composition in Culprit and Stable Lesions in Acute Coronary Syndrome and Stable Lesions in Stable Angina by Multidetector Computed Tomography
Udo Hoffmann, MD*,*,
Fabian Moselewski, BS*, ,
Koen Nieman, MD*,,
Ik-Kyung Jang, MD, PhD,
Maros Ferencik, MD, PhD*,
Ayaz M. Rahman, MD*,
Ricardo C. Cury, MD*,
Suhny Abbara, MD*,
Hamid Joneidi-Jafari, BS*,
Stephan Achenbach, MD*,, and
Thomas J. Brady, MD*
* Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
Department of Internal Medicine II, University of Erlangen, Erlangen, Germany
Manuscript received June 13, 2005;
revised manuscript received September 25, 2005,
accepted November 9, 2005.
* Reprint requests and correspondence: Dr. Udo Hoffmann, Department of Radiology, Massachusetts General Hospital, 165 Charles River Plaza, Suite 400, Boston, Massachusetts 02114. (Email: uhoffmann{at}partners.org).
OBJECTIVES: The purpose of this study was to assess morphology and composition of culprit and stable coronary lesions by multidetector computed tomography (MDCT).
BACKGROUND: Noninvasive identification of culprit lesions has the potential to improve noninvasive risk stratification in patients with acute chest pain.
METHODS: Thirty-seven patients with acute coronary syndrome (ACS) or stable angina underwent coronary 16-slice MDCT and invasive selective angiography. In all significant coronary lesions two observers measured the degree of stenosis, plaque area at stenosis, and remodeling index and assessed plaque composition. Differences between culprit lesions in patients with ACS and stable lesions in patients with ACS or stable angina were determined.
RESULTS: We analyzed 40 lesions with excellent image quality in 14 patients with ACS and 9 patients with stable angina. Culprit lesions in patients with ACS (n = 14) had significantly greater plaque area and a higher remodeling index than both stable lesions in patients with ACS (n = 13) and in patients with stable angina (n = 13) (17.5 ± 5.9 mm2 vs. 9.1 ± 4.8 mm2 vs. 13.5 ± 10.7 mm2, p = 0.02; and 1.4 ± 0.3 vs. 1.0 ± 0.4 vs. 1.2 ± 0.3, p = 0.04, respectively). The prevalence of non-calcified plaque was 100%, 62%, and 77%, respectively, and the prevalence of calcified plaque was 71%, 92%, and 85%, respectively, in culprit lesions in patients with ACS and in stable lesions in patients with ACS or stable angina.
CONCLUSIONS: We introduce the concept of noninvasive detection and characterization of coronary atherosclerotic lesions in patients with ACS by MDCT. We identified differences in lesion morphology and plaque composition between culprit lesions in ACS and stable lesions in ACS or stable angina, consistent with previous intravascular ultrasound studies.
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Abbreviations and Acronyms
| | ACS = acute coronary syndrome | | CT = computed tomography | | ECG = electrocardiogram | | HU = Hounsfield units | | IVUS = intravascular ultrasound | | LAD = left anterior descending (coronary artery) | | LCX = left circumflex | | LM = left main (coronary artery) | | MDCT = multidetector computed tomography | | NSTEMI = non–ST-segment elevation myocardial infarction | | RCA = right coronary artery | | RI = remodeling index |
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January 26, 2012;
(2012)
ehs006v1.
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. B. J. Mancini, P. M. Hartigan, E. R. Bates, S. P. Sedlis, D. J. Maron, J. A. Spertus, D. S. Berman, W. J. Kostuk, L. J. Shaw, W. S. Weintraub, et al.
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Circ Cardiovasc Interv,
December 1, 2011;
4(6):
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[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. J. de Feijter and K. Nieman
Failure of CT coronary imaging to identify plaque erosion: a resetting of expectations
Eur. Heart J.,
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32(22):
2736 - 2738.
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Ozaki, M. Okumura, T. F. Ismail, S. Motoyama, H. Naruse, K. Hattori, H. Kawai, M. Sarai, Y. Takagi, J. Ishii, et al.
Coronary CT angiographic characteristics of culprit lesions in acute coronary syndromes not related to plaque rupture as defined by optical coherence tomography and angioscopy
Eur. Heart J.,
November 2, 2011;
32(22):
2814 - 2823.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. J. Menezes, C. W. Kotze, O. Agu, T. Richards, J. Brookes, V. J. Goh, M. Rodriguez-Justo, R. Endozo, R. Harvey, S. W. Yusuf, et al.
Investigating Vulnerable Atheroma Using Combined 18F-FDG PET/CT Angiography of Carotid Plaque with Immunohistochemical Validation
J. Nucl. Med.,
November 1, 2011;
52(11):
1698 - 1703.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Stolzmann, S. Subramanian, A. Abdelbaky, P. Maurovich-Horvat, H. Scheffel, A. Tawakol, and U. Hoffmann
Complementary Value of Cardiac FDG PET and CT for the Characterization of Atherosclerotic Disease
RadioGraphics,
September 1, 2011;
31(5):
1255 - 1269.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. W. Nance Jr, F. Bamberg, U. J. Schoepf, D. K. Kang, J. M. Barraza Jr, J. A. Abro, G. Bastarrika, G. F. Headden, P. Costello, and C. Thilo
Coronary Atherosclerosis in African American and White Patients with Acute Chest Pain: Characterization with Coronary CT Angiography
Radiology,
August 1, 2011;
260(2):
373 - 380.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. S. Kristensen, K. F. Kofoed, J. T. Kuhl, W. B. Nielsen, M. B. Nielsen, and H. Kelbaek
Prognostic Implications of Nonobstructive Coronary Plaques in Patients With Non-ST-Segment Elevation Myocardial Infarction: A Multidetector Computed Tomography Study
J. Am. Coll. Cardiol.,
July 26, 2011;
58(5):
502 - 509.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. A. Neefjes, G.-J. R. ten Kate, A. Rossi, A. J. Galema-Boers, J. G. Langendonk, A. C. Weustink, A. Moelker, K. Nieman, N. R. Mollet, G. P. Krestin, et al.
CT coronary plaque burden in asymptomatic patients with familial hypercholesterolaemia
Heart,
July 15, 2011;
97(14):
1151 - 1157.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Gauss, S. Achenbach, T. Pflederer, A. Schuhback, W. G. Daniel, and M. Marwan
Assessment of coronary artery remodelling by dual-source CT: a head-to-head comparison with intravascular ultrasound
Heart,
June 15, 2011;
97(12):
991 - 997.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
F. Bamberg, W. H. Sommer, V. Hoffmann, S. Achenbach, K. Nikolaou, D. Conen, M. F. Reiser, U. Hoffmann, and C. R. Becker
Meta-Analysis and Systematic Review of the Long-Term Predictive Value of Assessment of Coronary Atherosclerosis by Contrast-Enhanced Coronary Computed Tomography Angiography
J. Am. Coll. Cardiol.,
June 14, 2011;
57(24):
2426 - 2436.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
F. Hyafil, E. Vucic, J.-C. Cornily, R. Sharma, V. Amirbekian, F. Blackwell, E. Lancelot, C. Corot, V. Fuster, Z. S. Galis, et al.
Monitoring of arterial wall remodelling in atherosclerotic rabbits with a magnetic resonance imaging contrast agent binding to matrix metalloproteinases
Eur. Heart J.,
June 2, 2011;
32(12):
1561 - 1571.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Vancraeynest, A. Pasquet, V. Roelants, B. L. Gerber, and J.-L. J. Vanoverschelde
Imaging the Vulnerable Plaque
J. Am. Coll. Cardiol.,
May 17, 2011;
57(20):
1961 - 1979.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Voros, S. Rinehart, Z. Qian, P. Joshi, G. Vazquez, C. Fischer, P. Belur, E. Hulten, and T. C. Villines
Coronary Atherosclerosis Imaging by Coronary CT Angiography: Current Status, Correlation With Intravascular Interrogation and Meta-Analysis
J. Am. Coll. Cardiol. Img.,
May 1, 2011;
4(5):
537 - 548.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. M. Ridker
High-Sensitivity C-Reactive Protein, Vascular Imaging, and Vulnerable Plaque: More Evidence to Support Trials of Antiinflammatory Therapy for Cardiovascular Risk Reduction
Circ Cardiovasc Imaging,
May 1, 2011;
4(3):
195 - 197.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Rubin, H.-J. Chang, K. Nasir, R. S. Blumenthal, M. J. Blaha, E.-K. Choi, S.-A. Chang, Y. E. Yoon, E. J. Chun, S.-i. Choi, et al.
Association Between High-Sensitivity C-Reactive Protein and Coronary Plaque Subtypes Assessed by 64-Slice Coronary Computed Tomography Angiography in an Asymptomatic Population
Circ Cardiovasc Imaging,
May 1, 2011;
4(3):
201 - 209.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Inoue, S. Motoyama, M. Sarai, T. Sato, H. Harigaya, T. Hara, Y. Sanda, H. Anno, T. Kondo, N. D. Wong, et al.
Serial Coronary CT Angiography-Verified Changes in Plaque Characteristics as an End Point: Evaluation of Effect of Statin Intervention
J. Am. Coll. Cardiol. Img.,
July 1, 2010;
3(7):
691 - 698.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. M. Johnson, J. M. Dennis, and D. A. Dowe
Extracardiac Findings on Coronary CT Angiograms: Limited Versus Complete Image Review
Am. J. Roentgenol.,
July 1, 2010;
195(1):
143 - 148.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. B. Mark, D. S. Berman, M. J. Budoff, J. J. Carr, T. C. Gerber, H. S. Hecht, M. A. Hlatky, J. M. Hodgson, M. S. Lauer, J. M. Miller, et al.
ACCF/ACR/AHA/NASCI/SAIP/SCAI/SCCT 2010 Expert Consensus Document on Coronary Computed Tomographic Angiography: A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents
J. Am. Coll. Cardiol.,
June 8, 2010;
55(23):
2663 - 2699.
[Full Text]
[PDF]
|
|
|
|
|
|
|
WRITING COMMITTEE MEMBERS, D. B. Mark, D. S. Berman, M. J. Budoff, J. J. Carr, T. C. Gerber, H. S. Hecht, M. A. Hlatky, J. M. Hodgson, M. S. Lauer, et al.
ACCF/ACR/AHA/NASCI/SAIP/SCAI/SCCT 2010 Expert Consensus Document on Coronary Computed Tomographic Angiography: A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents
Circulation,
June 8, 2010;
121(22):
2509 - 2543.
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Achenbach and P. Raggi
Imaging of coronary atherosclerosis by computed tomography
Eur. Heart J.,
June 2, 2010;
31(12):
1442 - 1448.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Maurovich-Horvat, U. Hoffmann, M. Vorpahl, M. Nakano, R. Virmani, and H. Alkadhi
The Napkin-Ring Sign: CT Signature of High-Risk Coronary Plaques?
J. Am. Coll. Cardiol. Img.,
April 1, 2010;
3(4):
440 - 444.
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Schepis, M. Marwan, T. Pflederer, M. Seltmann, D. Ropers, W. G. Daniel, and S. Achenbach
Quantification of non-calcified coronary atherosclerotic plaques with dual-source computed tomography: comparison with intravascular ultrasound
Heart,
April 1, 2010;
96(8):
610 - 615.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Kataiwa, K. Komukai, T. Tanimoto, K. Takemoto, S. Takarada, T. Kubo, et al.
Feasibility of Noninvasive Assessment of Thin-Cap Fibroatheroma by Multidetector Computed Tomography
J. Am. Coll. Cardiol. Img.,
December 1, 2009;
2(12):
1412 - 1419.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. M. van Werkhoven, J. D. Schuijf, O. Gaemperli, J. W. Jukema, L. J. Kroft, E. Boersma, A. Pazhenkottil, I. Valenta, G. Pundziute, A. de Roos, et al.
Incremental prognostic value of multi-slice computed tomography coronary angiography over coronary artery calcium scoring in patients with suspected coronary artery disease
Eur. Heart J.,
November 1, 2009;
30(21):
2622 - 2629.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. M. Matter, M. Stuber, and M. Nahrendorf
Imaging of the unstable plaque: how far have we got?
Eur. Heart J.,
November 1, 2009;
30(21):
2566 - 2574.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Bastarrika, Y. S. Lee, W. Huda, B. Ruzsics, P. Costello, and U. J. Schoepf
CT of Coronary Artery Disease
Radiology,
November 1, 2009;
253(2):
317 - 338.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Nagao, H. Matsuoka, H. Kawakami, H. Higashino, T. Mochizuki, M. Uemura, and S. Shigemi
Myocardial Ischemia in Acute Coronary Syndrome: Assessment Using 64-MDCT
Am. J. Roentgenol.,
October 1, 2009;
193(4):
1097 - 1106.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Djaberi, J. D. Schuijf, E. Boersma, L. J.M. Kroft, A. M. Pereira, J. A. Romijn, A. J. Scholte, J. W. Jukema, and J. J. Bax
Differences in Atherosclerotic Plaque Burden and Morphology Between Type 1 and 2 Diabetes as Assessed by Multislice Computed Tomography
Diabetes Care,
August 1, 2009;
32(8):
1507 - 1512.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M Marwan, D Ropers, T Pflederer, W G Daniel, and S Achenbach
Clinical characteristics of patients with obstructive coronary lesions in the absence of coronary calcification: an evaluation by coronary CT angiography
Heart,
July 1, 2009;
95(13):
1056 - 1060.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Motoyama, M. Sarai, H. Harigaya, H. Anno, K. Inoue, T. Hara, H. Naruse, J. Ishii, H. Hishida, N. D. Wong, et al.
Computed Tomographic Angiography Characteristics of Atherosclerotic Plaques Subsequently Resulting in Acute Coronary Syndrome
J. Am. Coll. Cardiol.,
June 30, 2009;
54(1):
49 - 57.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
U. Hoffmann and F. Bamberg
Is Computed Tomography Coronary Angiography the Most Accurate and Effective Noninvasive Imaging Tool to Evaluate Patients With Acute Chest Pain in the Emergency Department?: CT Coronary Angiography Is the Most Accurate and Effective Noninvasive Imaging Tool for Evaluating Patients Presenting With Chest Pain to the Emergency Department
Circ Cardiovasc Imaging,
May 1, 2009;
2(3):
251 - 263.
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. C. Hendel
Is Computed Tomography Coronary Angiography the Most Accurate and Effective Noninvasive Imaging Tool to Evaluate Patients With Acute Chest Pain in the Emergency Department?: CT Coronary Angiography Is the Most Accurate and Effective Noninvasive Imaging Tool for Evaluating Patients Presenting With Chest Pain to the Emergency Department: Antagonist Viewpoint
Circ Cardiovasc Imaging,
May 1, 2009;
2(3):
264 - 275.
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. Sundaram, S. Patel, P. Agarwal, and E. A. Kazerooni
Anatomy and Terminology for the Interpretation and Reporting of Cardiac MDCT: Part 2, CT Angiography, Cardiac Function Assessment, and Noncoronary and Extracardiac Findings
Am. J. Roentgenol.,
March 1, 2009;
192(3):
584 - 598.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Kitagawa, H. Yamamoto, J. Horiguchi, N. Ohhashi, F. Tadehara, T. Shokawa, Y. Dohi, E. Kunita, H. Utsunomiya, N. Kohno, et al.
Characterization of noncalcified coronary plaques and identification of culprit lesions in patients with acute coronary syndrome by 64-slice computed tomography.
J. Am. Coll. Cardiol. Img.,
February 1, 2009;
2(2):
153 - 160.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. J. de Feyter, S. Achenbach, and K. Nieman
CHAPTER 6 Cardiovascular Computed Tomography
ESC Textbook of Cardiovascular Medicine,
January 1, 2009;
2(1):
med-9780199566990-chapter - med-9780199566990-chapter.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. A. Rumberger
Coronary Computed Tomography Angiography: Our Time Has Come, But There Are Miles to Go Before We Sleep
J. Am. Coll. Cardiol.,
November 18, 2008;
52(21):
1733 - 1735.
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Aldrovandi, F. Cademartiri, A. Menozzi, F. Ugo, D. Lina, E. Maffei, A. Palumbo, M. Fusaro, G. Crisi, and D. Ardissino
Evaluation of Coronary Atherosclerosis by Multislice Computed Tomography in Patients With Acute Myocardial Infarction and Without Significant Coronary Artery Stenosis: A Comparative Study With Quantitative Coronary Angiography
Circ Cardiovasc Imaging,
November 1, 2008;
1(3):
205 - 211.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. K. Min and L. J. Shaw
Noninvasive Diagnostic and Prognostic Assessment of Individuals With Suspected Coronary Artery Disease: Coronary Computed Tomographic Angiography Perspective
Circ Cardiovasc Imaging,
November 1, 2008;
1(3):
270 - 281.
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Pundziute, J. D. Schuijf, J. W. Jukema, I. Decramer, G. Sarno, P. K. Vanhoenacker, E. Boersma, J. H.C. Reiber, M. J. Schalij, W. Wijns, et al.
Evaluation of plaque characteristics in acute coronary syndromes: non-invasive assessment with multi-slice computed tomography and invasive evaluation with intravascular ultrasound radiofrequency data analysis
Eur. Heart J.,
October 1, 2008;
29(19):
2373 - 2381.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Sarwar, J. Rieber, E. A. Q. Mooyaart, S. K. Seneviratne, S. L. Houser, F. Bamberg, O. C. Raffel, R. Gupta, M. K. Kalra, H. Pien, et al.
Calcified Plaque: Measurement of Area at Thin-Section Flat-Panel CT and 64-Section Multidetector CT and Comparison with Histopathologic Findings1
Radiology,
October 1, 2008;
249(1):
301 - 306.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. D. Dodd, J. Rieber, E. Pomerantsev, V. Chaithiraphan, S. Achenbach, J. M. Moreiras, S. Abbara, U. Hoffmann, T. J. Brady, and R. C. Cury
Quantification of Nonculprit Coronary Lesions: Comparison of Cardiac 64-MDCT and Invasive Coronary Angiography
Am. J. Roentgenol.,
August 1, 2008;
191(2):
432 - 438.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. J. Duerinckx
The Nonculprit Coronary Lesion as Seen by Coronary CT Angiography: What Should We Be Looking For?
Am. J. Roentgenol.,
August 1, 2008;
191(2):
439 - 440.
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. M. Henneman, J. D. Schuijf, G. Pundziute, J. M. van Werkhoven, E. E. van der Wall, J. W. Jukema, and J. J. Bax
Noninvasive Evaluation With Multislice Computed Tomography in Suspected Acute Coronary Syndrome: Plaque Morphology on Multislice Computed Tomography Versus Coronary Calcium Score
J. Am. Coll. Cardiol.,
July 15, 2008;
52(3):
216 - 222.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Pundziute, J. D. Schuijf, J. W. Jukema, I. Decramer, G. Sarno, P. K. Vanhoenacker, J. H.C. Reiber, M. J. Schalij, W. Wijns, and J. J. Bax
Head-to-Head Comparison of Coronary Plaque Evaluation Between Multislice Computed Tomography and Intravascular Ultrasound Radiofrequency Data Analysis
J. Am. Coll. Cardiol. Intv.,
April 1, 2008;
1(2):
176 - 182.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
F. Bamberg, N. Dannemann, M. D. Shapiro, S. K. Seneviratne, M. Ferencik, J. Butler, W. Koenig, K. Nasir, R. C. Cury, A. Tawakol, et al.
Association Between Cardiovascular Risk Profiles and the Presence and Extent of Different Types of Coronary Atherosclerotic Plaque as Detected by Multidetector Computed Tomography
Arterioscler Thromb Vasc Biol,
March 1, 2008;
28(3):
568 - 574.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Schroeder, S. Achenbach, F. Bengel, C. Burgstahler, F. Cademartiri, P. de Feyter, R. George, P. Kaufmann, A. F. Kopp, J. Knuuti, et al.
Cardiac computed tomography: indications, applications, limitations, and training requirements: Report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology
Eur. Heart J.,
February 2, 2008;
29(4):
531 - 556.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. T. Wilson, P. Gopalakrishnan, and T. Tak
Noninvasive Cardiac Imaging with Computed Tomography
Clin. Med. Res.,
October 1, 2007;
5(3):
165 - 171.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Motoyama, T. Kondo, M. Sarai, A. Sugiura, H. Harigaya, T. Sato, K. Inoue, M. Okumura, J. Ishii, H. Anno, et al.
Multislice Computed Tomographic Characteristics of Coronary Lesions in Acute Coronary Syndromes
J. Am. Coll. Cardiol.,
July 24, 2007;
50(4):
319 - 326.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. D. Schuijf, G. Pundziute, and J. J. Bax
Reply
J. Am. Coll. Cardiol.,
May 22, 2007;
49(20):
2071 - 2071.
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. S. Lewis and D. A. Halon
Integrating Multidetector Computed Tomography Into Clinical Practice: Computed Tomography Scanning Shows its Metal
J. Am. Coll. Cardiol.,
March 6, 2007;
49(9):
960 - 962.
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. J. Pepine, W. W. Nichols, and D. F. Pauly
Estrogen and Different Aspects of Vascular Disease in Women and Men
Circ. Res.,
September 1, 2006;
99(5):
459 - 461.
[Full Text]
[PDF]
|
|
|
|
